Transplantation of neural stem cells improves recovery of stroke-affected mice and induces cell-specific changes in GSDMD and MLKL expression
NSC transplantation holds therapeutic potential in stroke recovery by targeting pyroptosis and necroptosis pathways. These findings shed light on the mechanisms underlying NSC-mediated neuroprotection and support their further exploration as a promising therapy for stroke patients.
Authors
- Ivan Alić (ORCID: https://orcid.org/0000-0002-8125-8198)
- Iva Šimunić (ORCID: https://orcid.org/0000-0002-4411-0194)
- Damir Lisjak
- Dinko Mitrečić (ORCID: https://orcid.org/0000-0003-4836-1721)
Institutions
- University of Zagreb (HR)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2024-08-15
- DOI
- https://doi.org/10.3389/fnmol.2024.1439994
- Citations
- 3
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- European Commission
- Hrvatska Zaklada za Znanost
- European Regional Development Fund