High expression of SIGLEC7 may promote M2-type macrophage polarization leading to adverse prognosis in glioma patients
High SIGLEC7 expression predicts poor prognosis in glioma patients and is closely associated with M2 macrophages in the tumor environment. In the future, SIGLEC7 may become a promising target for glioma immunotherapy.
Authors
- Yihua An (ORCID: https://orcid.org/0000-0003-0033-2999)
- Peishen Wang
- Zhiqiang Qiu (ORCID: https://orcid.org/0000-0002-9690-3655)
- Shouwei Li (ORCID: https://orcid.org/0000-0003-3320-2517)
- Changyuan Ren
- Lei Yuan (ORCID: https://orcid.org/0000-0001-5455-9529)
- Xinye Han
- Zi He
- Yanwen Cheng (ORCID: https://orcid.org/0009-0000-1355-8239)
- Wenhao An
Institutions
- Capital Medical University (CN)
- Beijing Sanbo Brain Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- Hainan Medical University (CN)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-08-15
- DOI
- https://doi.org/10.3389/fimmu.2024.1411072
- Citations
- 8
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.92