Network medicine analysis for dissecting the therapeutic mechanism of consensus TCM formulae in treating hepatocellular carcinoma with different TCM syndromes
The identification of these key compounds underscores the potential of network medicine to unravel the complex pharmacological actions of TCM. This study provides a molecular basis for TCM's therapeutic strategies in HCC and highlights specific herbal ingredients as potential leads for drug development and precision medicine.
Authors
- Yi Zhao (ORCID: https://orcid.org/0000-0001-6046-8420)
- Lei Dong (ORCID: https://orcid.org/0000-0003-2097-6679)
- Wanchen Cao
- Jini Song
- Jincheng Guo (ORCID: https://orcid.org/0000-0002-5616-6910)
- Yang Wu (ORCID: https://orcid.org/0000-0001-6547-9524)
- Zihao He (ORCID: https://orcid.org/0000-0001-6588-1169)
- Liu Liu (ORCID: https://orcid.org/0000-0001-9852-570X)
- Kai Gao (ORCID: https://orcid.org/0000-0003-1375-1295)
Institutions
- Arkansas State University (US)
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Sciences (CN)
- Institute of Computing Technology (CN)
- New York Institute of Technology (US)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-08-15
- DOI
- https://doi.org/10.3389/fendo.2024.1373054
- Citations
- 4
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province