Ocrelizumab in MS patients with persistence of disease activity after alemtuzumab: A multi-center Italian study
OCR after two ALM courses seemed to be safe and effective. Early IgM hypogammaglobulinemia occurred in a high proportion of patients. The evidence of inflammatory activity between ALM courses seemed to increase the risk of MS re-activation on OCR treatment.
Authors
- Giancarlo Coghe (ORCID: https://orcid.org/0000-0002-3796-3279)
- Mauro Zaffaroni (ORCID: https://orcid.org/0000-0001-9020-934X)
- Carolina Gabri Nicoletti (ORCID: https://orcid.org/0000-0003-3361-8141)
- Lucia Moiola (ORCID: https://orcid.org/0000-0001-6313-4952)
- Girolama Alessandra Marfia (ORCID: https://orcid.org/0000-0001-5863-7758)
- Federica Pinardi
- Maria Cellerino (ORCID: https://orcid.org/0000-0002-4359-9872)
- Jessica Frau (ORCID: https://orcid.org/0000-0001-9068-9144)
- Massimiliano Mirabella (ORCID: https://orcid.org/0000-0002-7783-114X)
- Marco Vercellino (ORCID: https://orcid.org/0000-0002-4199-3884)
- Valentina Torri Clerici (ORCID: https://orcid.org/0000-0002-7336-6340)
- Marco Ronzoni
- Agostino Nozzolillo
- E Deloya Tomas
- Antonio Uccelli (ORCID: https://orcid.org/0000-0002-2008-6038)
- Paola Grossi (ORCID: https://orcid.org/0000-0003-1581-0623)
- Maria Petracca (ORCID: https://orcid.org/0000-0001-9429-2769)
- Roberta Lanzillo (ORCID: https://orcid.org/0000-0001-6388-8180)
- Matilde Inglese (ORCID: https://orcid.org/0000-0002-9610-0297)
- Paola Cavalla (ORCID: https://orcid.org/0000-0003-4589-4864)
- Giovanni Novi (ORCID: https://orcid.org/0000-0003-3877-6763)
- Caterina Lapucci (ORCID: https://orcid.org/0000-0002-3527-6520)
- Assunta Bianco (ORCID: https://orcid.org/0000-0002-7101-0949)
- Eleonora E. Cocco (ORCID: https://orcid.org/0000-0002-3878-8820)
- Vincenzo Brescia Morra (ORCID: https://orcid.org/0000-0003-0462-9618)
- Maria Teresa Ferrò (ORCID: https://orcid.org/0000-0003-1888-3510)
- Doriana Landi
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Rome Tor Vergata (IT)
- Vita-Salute San Raffaele University (IT)
- University of Cagliari (IT)
- Agostino Gemelli University Polyclinic (IT)
- Regione Puglia (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Ospedale Policlinico San Martino (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- Azienda Socio Sanitaria Territoriale della Valle Olona
- Aziende Socio Sanitaria Territoriale Rhodense
- University of Naples Federico II (IT)
- University of Genoa (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Multiple Sclerosis Journal
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1177/13524585241266509
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondazione Italiana Sclerosi Multipla
- Ministero della Salute