The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei
Seven proteins identified by screening affect P. berghei sexual development, suggesting that phosphatase inhibitors can be used for functional protein screening.
Authors
- Jinghan Lu (ORCID: https://orcid.org/0009-0007-5653-2646)
- Meilian Wang (ORCID: https://orcid.org/0000-0003-3854-9755)
- Hui Min (ORCID: https://orcid.org/0000-0003-2667-7864)
- Xitong Jia
- Jiao Li (ORCID: https://orcid.org/0000-0002-0323-3710)
- Lunhao Bai (ORCID: https://orcid.org/0000-0003-2135-8987)
- Haifeng Lu (ORCID: https://orcid.org/0000-0003-2886-5615)
- Yaming Cao
- Zehou Fang
- Yong Wang (ORCID: https://orcid.org/0009-0001-0305-2995)
Institutions
- China Medical University (CN)
Publication Details
- Journal
- International Journal for Parasitology Drugs and Drug Resistance
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1016/j.ijpddr.2024.100563
- Primary Topic
- Invertebrate Immune Response Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Allergy and Infectious Diseases