Analysis of PANoptosis-related ceRNA network reveals lncRNA MIR17HG involved in osteogenic differentiation inhibition impaired by tumor necrosis factor-α
Our data suggest that TNF-α-induced inhibition of osteogenic differentiation and PANoptosis in MC3T3-E1 osteoblasts is associated with MIR17HG. These findings highlight the critical role of MIR17HG in the interplay between inflammation, PANoptosis, and osteogenic differentiation, suggesting potential therapeutic targets for conditions involving impaired bone formation and inflammatory responses.
Authors
- Wei Zhang (ORCID: https://orcid.org/0000-0002-5111-4097)
- Chang-Liang Xia
- Jia-Xuan Li (ORCID: https://orcid.org/0000-0002-0790-0947)
- Yudun Qu (ORCID: https://orcid.org/0000-0002-0905-2937)
- Changpeng Xu
- Yong Qi (ORCID: https://orcid.org/0000-0002-2653-1307)
- Shuanji Ou
- Yang� Yang (ORCID: https://orcid.org/0000-0003-1222-1209)
- Songsong Wang (ORCID: https://orcid.org/0000-0003-0528-7920)
Institutions
- Jinan University (CN)
- Xiamen University (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1007/s11033-024-09810-0
- Citations
- 8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 2.28
Funders
- National Natural Science Foundation of China