Meldonium, as a potential neuroprotective agent, promotes neuronal survival by protecting mitochondria in cerebral ischemia–reperfusion injury
Our study demonstrated that meldonium shows a neuroprotective function during CIRI by preserving the mitochondrial function, thus prevented neurons from apoptosis.
Authors
- Weidong Li (ORCID: https://orcid.org/0000-0002-7664-1512)
- Xin Sui
- Weijie Yang
- Jun Yang (ORCID: https://orcid.org/0000-0002-1943-3979)
- Zhenghao Bao
- Yangyang Sun (ORCID: https://orcid.org/0000-0002-4357-611X)
- Yuan Luo (ORCID: https://orcid.org/0000-0002-3137-916X)
- Zhenyu Xiao
- Xinyi Yang (ORCID: https://orcid.org/0000-0003-2638-5482)
- Fengying Liu
- Yi Yang (ORCID: https://orcid.org/0000-0003-0621-7596)
- Yongan Wang
- Xueyang Lin
- Ziqi cui
- Yingkai Ma
- Xiuxing Lei
Institutions
- Institute of Pharmacology (CZ)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1186/s12967-024-05222-7
- Citations
- 11
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- National Natural Science Foundation of China