Cross-sectional Assessment of Physical Manifestations in Vietnamese Children with Thalassemia: A Single-Center Study

Introduction:This cross-sectional study intends to analyze the physical growth of children thalassemia patients and evaluate the factors linked to their physical features.Materials and methods: This cross-sectional study tracked 44 pediatric thalassemia patients at a Central Vietnam Tertiary Pediatric Center from February to December 2023. Results:The study participants had a mean age of 7.5 4.3 years and an equal gender distribution.64.5% of these individuals had thalassemia and required blood transfusions.43.2% of subjects had serum ferritin levels above 1000 ng/ml, and the average hemoglobin content was 67.4 16.1 g/L 31.8% of the children assessed had height-for-age measurements below -2 standard deviations, while 43.2% had weight-for-age measurements below -2 standard deviations.Significant correlations were found between height-for-age, weight-for-age, blood transfusion reliance, and serum ferritin levels (p < 0.05).No significant changes were seen between physical indices and disease type or hemoglobin concentration (p > 0.05).31.8% of juvenile thalassemia patients were found to have stunting, whereas 43.2% exhibited wasting malnutrition in this study.Conclusion: Blood transfusion reliance and serum ferritin concentration were found to be linked to a higher occurrence of stunting and wasting malnutrition in children with thalassemia zGiri: almann amac, talasemili hastas ocuklarn fiziksel bymesini analiz etmek ve fiziksel zellikleriyle ilikili faktrleri deerlendirmektir.Yntem Ve Gereler: Bu almada ubat-Aralk 2023 tarihleri arasnda Orta Vietnam'daki nc Basamak ocuk Sal Merkezinde 44 talasemili ocuk hasta apraz kesitsel olarak takip edildi.Bulgular: almaya katlanlarn ortalama ya 7,5 4,3 yl olup cinsiyet dalmlar eitti.Bu bireylerin %64,5'i talasemi hastasyd ve kan transfzyonuna ihtiya duyuyordu.Deneklerin %43,2'sinde serum ferritin dzeyleri 1000 ng/ml'nin zerindeydi ve ortalama hemoglobin ierii 67,4 16,1 g/L idi.Deerlendirilen ocuklarn %31,8'inin boy/ya lmleri -2 standart sapmann altnda, %43,2'sinin ise arlk