AB029. Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis

Our mitochondria-targeted treatment was effective for cells with both glucose-starved conditions and normoglycemic conditions. It is necessary to investigate its effectiveness in vivo in the future. However, chloramphenicol has already been used, and therefore, this treatment can be used for humans safely. This discovery is expected to make a major contribution to the development of treatments for glioblastomas.

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Publication Details

Journal
Chinese Clinical Oncology
Published
2024-08-01
DOI
https://doi.org/10.21037/cco-24-ab029
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

AB029. Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis

Daisuke Kuga, Koji Yoshimoto, Takeshi Uchiumi, Yuya Kunisaki et al.
Chinese Clinical Oncology
Ferroptosis and cancer prognosis
article

AB029. Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis

Daisuke Kuga, Koji Yoshimoto, Takeshi Uchiumi, Yuya Kunisaki, Ryusuke Hatae, Mikako Yagi, K. Miki
article en

Abstract

Our mitochondria-targeted treatment was effective for cells with both glucose-starved conditions and normoglycemic conditions. It is necessary to investigate its effectiveness in vivo in the future. However, chloramphenicol has already been used, and therefore, this treatment can be used for humans safely. This discovery is expected to make a major contribution to the development of treatments for glioblastomas.

Chinese Clinical OncologyVol. 13(Suppl 1)
Kyushu University (JP)
Openalex Percentile: Top 76%
Ferroptosis and cancer prognosis
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