Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report

This case report describes a rare presentation of gastrointestinal stromal tumor (GIST) causing mechanical small bowel obstruction in a 30-yearold female patient with a history of hepatitis B. Initial misdiagnosis as gastritis led to delayed recognition of the underlying pathology.Emergency laparoscopic intervention revealed mixed epithelioid and spindle cell GIST with high risk features, prompting segmental small bowel resection.Histopathological examination confirmed a PDGFRA mutation, loss of c-kit and DOG 1 expression, and a high mitotic rate, categorizing the tumor as high risk.This case highlights the importance of considering GIST in the differential diagnosis of abdominal symptoms and emphasizes the need for timely intervention to prevent complications.

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Publication Details

Journal
Caucasian Medical Journal
Published
2024-08-15
DOI
https://doi.org/10.4274/cmj.galenos.2024.54254
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report

Steffen Seyfried, Zamin Adigozalli, Rasim Khalilov
Caucasian Medical Journal
Gastrointestinal Tumor Research and Treatment
article

Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report

Steffen Seyfried, Zamin Adigozalli, Rasim Khalilov
article en

Abstract

This case report describes a rare presentation of gastrointestinal stromal tumor (GIST) causing mechanical small bowel obstruction in a 30-yearold female patient with a history of hepatitis B. Initial misdiagnosis as gastritis led to delayed recognition of the underlying pathology.Emergency laparoscopic intervention revealed mixed epithelioid and spindle cell GIST with high risk features, prompting segmental small bowel resection.Histopathological examination confirmed a PDGFRA mutation, loss of c-kit and DOG 1 expression, and a high mitotic rate, categorizing the tumor as high risk.This case highlights the importance of considering GIST in the differential diagnosis of abdominal symptoms and emphasizes the need for timely intervention to prevent complications.

Caucasian Medical Journal
Azerbaijan Medical University (AZ), Heidelberg University (DE), University Medical Centre Mannheim (DE)
Good health and well-being
Openalex Percentile: Top 76%
Gastrointestinal Tumor Research and Treatment
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