Half of oncologists fail to use ordered NGS results to guide their first-line treatment decision in advanced NSCLC: A retrospective study in a community-based integrated healthcare system

NGS tests results were not exclusively used to inform first line treatment decisions in most patients with stage IV NSCLC, and most patients with a targetable mutation were not treated with targeted therapy. Possible explanations include lengthy turnaround times for NGS testing and the availability of timelier but less accurate single gene testing.

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Publication Details

Journal
Heliyon
Published
2024-08-01
DOI
https://doi.org/10.1016/j.heliyon.2024.e36308
Citations
2
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.84

Funders

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article

Half of oncologists fail to use ordered NGS results to guide their first-line treatment decision in advanced NSCLC: A retrospective study in a community-based integrated healthcare system

Dominick Zheng, Reina Haque, Lie Hong Chen, Eric C. McGary et al.
2 citations
Heliyon
Lung Cancer Treatments and Mutations
0.84
article

Half of oncologists fail to use ordered NGS results to guide their first-line treatment decision in advanced NSCLC: A retrospective study in a community-based integrated healthcare system

Dominick Zheng, Reina Haque, Lie Hong Chen, Eric C. McGary, Ahmed I. Megahed
article en
2 citations

Abstract

NGS tests results were not exclusively used to inform first line treatment decisions in most patients with stage IV NSCLC, and most patients with a targetable mutation were not treated with targeted therapy. Possible explanations include lengthy turnaround times for NGS testing and the availability of timelier but less accurate single gene testing.

HeliyonVol. 10(16)
Kaiser Permanente (US)
Kaiser Permanente, Kaiser Permanente Washington Health Research Institute
Openalex Percentile: Top 25%
Lung Cancer Treatments and Mutations
0.84
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