AVANÇOS CLÍNICOS NO USO DE PSICODÉLICOS PARA TRANSTORNOS PSIQUIÁTRICOS: UMA REVISÃO INTEGRATIVA

This integrative review explores the use of psychedelics in psychiatry, focusing on their historical context, recent resurgence, and clinical efficacy in treating psychiatric disorders such as depression, PTSD, and anxiety. Initially, psychedelic therapies showed promise in the 1950s and 1970s but were diminished due to restrictive policies and stigma. However, a resurgence in clinical interest has been driven by new research and changing public perceptions, highlighting the potential effectiveness of psychedelics compared to traditional treatments, which are often ineffective or have significant side effects. The review discusses the mechanisms of action and neuroplasticity induced by psychedelics, integrative therapeutic approaches, and the associated risks and ethical challenges. The future of psychedelic therapies appears promising, with advancements in research and regulatory changes potentially expanding their clinical applications. The review concludes with a reflection on clinical practice implications and suggestions for future research areas.