Expression and prognosis of DSG-2, CXADR, CD46 in head and neck squamous cell carcinoma
No prognostic significance of the expression of DSG-2, CXADR or CD46 in HNSCC was seen. DSG-2, CXADR and CD46 are expressed in HNSCC, so that optimization of oncotherapy with adenoviral vectors appears promising. Due to the significantly increased expression of DSG-2 and CXADR in advanced OPSCC tumors, there is potential for optimizing oncotherapy here in particular.
Authors
- Anja Ehrhardt (ORCID: https://orcid.org/0000-0002-6639-4888)
- Inga Marte Charlott Seuthe (ORCID: https://orcid.org/0000-0002-0295-5447)
- Markus Ruwe (ORCID: https://orcid.org/0009-0000-7675-0965)
- Sabine Eichhorn (ORCID: https://orcid.org/0000-0001-7877-7977)
- Jonas Jae‐Hyun Park (ORCID: https://orcid.org/0000-0002-4582-819X)
- Steffi Silling (ORCID: https://orcid.org/0000-0002-9555-3876)
- Eric Ehrke‐Schulz (ORCID: https://orcid.org/0000-0001-8154-9860)
- Lea Krause
Institutions
- FernUniversität in Hagen (DE)
- Witten/Herdecke University (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Pathology - Research and Practice
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1016/j.prp.2024.155541
- Citations
- 1
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.55