Clinical Validation of Human Papilloma Virus Circulating Tumor DNA for Early Detection of Residual Disease After Chemoradiation in Cervical Cancer
(Abstracted from J Clin Oncol 2023;42:431–440 The majority of cervical cancers are caused by human papillomavirus (HPV), and despite treatment with chemoradiation (CRT), up to 40% of patients with locally advanced cervical cancer will relapse. Current prognostic factors are poor predictors of relapse; however, detection of HPV circulating tumor DNA (ctDNA) after CRT may identify those at higher risk of relapse.
Authors
- Amandeep Taggar (ORCID: https://orcid.org/0000-0002-3562-5890)
- Eric Leung (ORCID: https://orcid.org/0000-0001-5730-8055)
- Jennifer Croke (ORCID: https://orcid.org/0000-0002-7090-6313)
- Jelena Lukovic
- Elizabeth Barnes (ORCID: https://orcid.org/0000-0002-4058-0236)
- Zeynep Baskurt (ORCID: https://orcid.org/0000-0002-0714-7406)
- Helen J MacKay (ORCID: https://orcid.org/0000-0001-6220-1789)
- Magali Lecavalier‐Barsoum (ORCID: https://orcid.org/0000-0002-0068-2764)
- Eve‐Lyne Marchand (ORCID: https://orcid.org/0009-0005-0618-3260)
- Yangqiao Zheng
- Lilian T. Gien (ORCID: https://orcid.org/0000-0002-6558-3337)
- Jinfeng Zou (ORCID: https://orcid.org/0000-0002-4309-0961)
- Scott V. Bratman (ORCID: https://orcid.org/0000-0001-8610-4908)
- Michael Milosevic (ORCID: https://orcid.org/0000-0002-9620-6876)
- Ur Metser (ORCID: https://orcid.org/0000-0003-3726-8994)
- Sarah E. Ferguson (ORCID: https://orcid.org/0000-0002-2123-3642)
- Adam Gladwish
- Anthony Fyles (ORCID: https://orcid.org/0000-0002-3633-2483)
- Zhen Zhao (ORCID: https://orcid.org/0000-0001-7127-3215)
- Stephanie Lheureux
- Kathy Han
Publication Details
- Journal
- Obstetrical & Gynecological Survey
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1097/01.ogx.0001050544.16643.94
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00