Atorvastatin inhibits Lipopolysaccharide (LPS)-induced vascular inflammation to protect endothelium by inducing Heme Oxygenase-1 (HO-1) expression
For LPS-induced vascular inflammation, high-dose atorvastatin exerts potent anti-inflammatory and vascular endothelial protection effects by inducing HO-1 expression.
Authors
- Keming Huang
- Gong Chen (ORCID: https://orcid.org/0009-0000-6477-381X)
- Gang Wei (ORCID: https://orcid.org/0000-0001-5839-1276)
- Jian Luo (ORCID: https://orcid.org/0000-0002-9756-3066)
- Qian Zhu
- Yongquan Peng
- Wen Xue (ORCID: https://orcid.org/0000-0002-0251-3489)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1371/journal.pone.0308823
- Citations
- 5
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Southwest Medical University