Profiling Cell-Free DNA from Malignant Pleural Effusion for Oncogenic Driver Mutations in Patients with Treatment-Naive Stage IV Adenocarcinoma: A Multicenter Prospective Study
Genotyping of MPE supernatant cfDNA is feasible in clinical practice, in addition to plasma and tumor testing, to improve diagnostic yield and extend patients' benefit from targeted therapies.
Authors
- Po‐Wei Hu (ORCID: https://orcid.org/0000-0002-4784-6324)
- Yu‐Feng Wei (ORCID: https://orcid.org/0000-0002-6380-3527)
- Jui-Chi Hung
- Chung‐Yu Chen (ORCID: https://orcid.org/0000-0001-9002-7255)
- Cheng‐Yu Chang (ORCID: https://orcid.org/0000-0002-7196-3504)
- Yi-Chun Lai (ORCID: https://orcid.org/0000-0002-4673-7492)
- Shih-Chieh Chang (ORCID: https://orcid.org/0009-0006-4470-1783)
Institutions
- National Yang Ming Chiao Tung University (TW)
- Far Eastern Memorial Hospital (TW)
- National Taiwan University Hospital (TW)
- National Yunlin University of Science and Technology (TW)
- National Taiwan Sport University (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Molecular Diagnosis & Therapy
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1007/s40291-024-00736-8
- Citations
- 6
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.71