Four new phenylpropanoid glycosides from the leaves of <i>Illicium dunnianum</i> and their neuroprotective activities

Four previously unreported phenylpropanoid glycosides (<b>1</b>-<b>4</b>), together with four known analogues (<b>5</b>-<b>8</b>), were isolated from the leaves of <i>Illicium dunnianum</i>. The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in H<sub>2</sub>O<sub>2</sub>-induced OLN-93 cell injury model.

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Publication Details

Journal
Natural Product Research
Published
2024-08-15
DOI
https://doi.org/10.1080/14786419.2024.2386396
Primary Topic
Magnolia and Illicium research
Type
article
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article

Four new phenylpropanoid glycosides from the leaves of Illicium dunnianum and their neuroprotective activities

Qian‐Qian Pang, Yang Yu, Xiaoqing He, Yong-wen Zhang et al.
Natural Product Research
Magnolia and Illicium research
article

Four new phenylpropanoid glycosides from the leaves of Illicium dunnianum and their neuroprotective activities

Qian‐Qian Pang, Yang Yu, Xiaoqing He, Yong-wen Zhang, Haibo Li, Zhenzhong Wang, Xin‐Sheng Yao
article en

Abstract

Four previously unreported phenylpropanoid glycosides (<b>1</b>-<b>4</b>), together with four known analogues (<b>5</b>-<b>8</b>), were isolated from the leaves of <i>Illicium dunnianum</i>. The structures of these new compounds were elucidated based on spectroscopic analysis (HR-ESI-MS, NMR, IR, UV) and chemical methods. In addition, the neuroprotective activities of all the isolates were evaluated by measuring their cell viability in H<sub>2</sub>O<sub>2</sub>-induced OLN-93 cell injury model.

Natural Product ResearchVol. 40(1)
Nanjing University of Chinese Medicine (CN), Jinan University (CN), Laboratoire de Chémo-biologie synthétique et thérapeutique (FR), Kanion Pharmaceutical (China) (CN), Ministry of Education (TH)
Zero hunger
Openalex Percentile: Top 84%
Magnolia and Illicium research
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Four new phenylpropanoid glycosides from the leaves of <i>Illicium dunnianum</i> and their neuroprotective activities — Qian‐Qian Pang, Yang Yu, et al. · Natural Product Research (2024) | TGRS Research Map | TGRS