Human adipose and synovial-derived MSCs synergistically attenuate osteoarthritis by promoting chondrocyte autophagy through FoxO1 signaling
A combination of human ADSCs and SDSCs demonstrated higher potential than a single type of stem cell, demonstrating potential as a novel treatment for OA.
Authors
- Qisong Liu (ORCID: https://orcid.org/0000-0003-3379-5308)
- Jianqun Wu (ORCID: https://orcid.org/0000-0002-6805-7746)
- Yonghao Pan (ORCID: https://orcid.org/0000-0003-2024-8874)
- Yangyi Yu (ORCID: https://orcid.org/0000-0003-0292-0954)
- Guangheng Li (ORCID: https://orcid.org/0000-0001-6368-7071)
- Yang Liu (ORCID: https://orcid.org/0000-0002-2226-0941)
- Chao Liu (ORCID: https://orcid.org/0000-0001-6637-1689)
- Kai Li (ORCID: https://orcid.org/0000-0003-1664-5439)
- Gui-ang Liu
- Qiang Lian
- Songqiang Huang (ORCID: https://orcid.org/0000-0003-0085-5765)
- Wenfeng Dai
Institutions
- Hunan University (CN)
- Southern University of Science and Technology (CN)
- ShenZhen People’s Hospital (CN)
- Shenzhen Luohu People's Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1186/s13287-024-03870-6
- Citations
- 12
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- National Natural Science Foundation of China
- Science, Technology and Innovation Commission of Shenzhen Municipality
- Southern University of Science and Technology