Sustainable N-Formylation of Anilines: Harnessing Aleuritic Acid as a Renewable Formyl Source

Abstract N-Formylation of anilines using a renewable aleuritic acid as an eco-friendly and sustainable formylating source has been developed. para-Substituted anilines generally provided good yields, while moderate yields were observed with meta- and ortho-substituted derivatives. In situ generated formic acid through oxidative cleavage of aleuritic acid serve as a formyl source, which has been confirmed through control experiments.

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Publication Details

Journal
Synlett
Published
2024-08-15
DOI
https://doi.org/10.1055/a-2388-9578
Primary Topic
Carbon dioxide utilization in catalysis
Type
article
Field-Weighted Citation Impact
0.00

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article

Sustainable N-Formylation of Anilines: Harnessing Aleuritic Acid as a Renewable Formyl Source

Gaurav Badhani, Subbarayappa Adimurthy, Hetavi A. Vadariya, B. Mohamed Farves et al.
Synlett
Carbon dioxide utilization in catalysis
article

Sustainable N-Formylation of Anilines: Harnessing Aleuritic Acid as a Renewable Formyl Source

Gaurav Badhani, Subbarayappa Adimurthy, Hetavi A. Vadariya, B. Mohamed Farves, Krupa N. Boda
article en

Abstract

Abstract N-Formylation of anilines using a renewable aleuritic acid as an eco-friendly and sustainable formylating source has been developed. para-Substituted anilines generally provided good yields, while moderate yields were observed with meta- and ortho-substituted derivatives. In situ generated formic acid through oxidative cleavage of aleuritic acid serve as a formyl source, which has been confirmed through control experiments.

SynlettVol. 35(20)
Central Salt and Marine Chemicals Research Institute (IN), Academy of Scientific and Innovative Research (IN)
Department of Science and Technology, Ministry of Science and Technology, India, Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research
Responsible consumption and production
Openalex Percentile: Top 91%
Carbon dioxide utilization in catalysis
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Sustainable N-Formylation of Anilines: Harnessing Aleuritic Acid as a Renewable Formyl Source — Gaurav Badhani, Subbarayappa Adimurthy, et al. · Synlett (2024) | TGRS Research Map | TGRS