Predictive performance of Metagenomic Next Generation Sequencing in early detection of post-liver transplantation infections
Despite the presence of false positives, mNGS still presents a potential advantage in predicting pulmonary infection pathogens following liver transplantation. Furthermore, the levels of CRP and CMV carrier status within four weeks post-surgery exhibit significant associations with patient survival and prognosis.
Authors
- Dongsheng Chen (ORCID: https://orcid.org/0000-0002-7196-4136)
- Jincheng Ma (ORCID: https://orcid.org/0000-0002-0144-8531)
- Zhuoyi Wang (ORCID: https://orcid.org/0000-0002-1058-2791)
- Chi Zhu
- Hengkai Zhu
- Siyi Zhong
- Dan Zhu
- Zhuang Li (ORCID: https://orcid.org/0000-0002-6940-5693)
- Shusen Zheng (ORCID: https://orcid.org/0000-0003-1459-8261)
- Zhe Yang (ORCID: https://orcid.org/0000-0003-1017-6328)
- Ran Ding (ORCID: https://orcid.org/0000-0002-7453-8968)
- Xiangyan Liu (ORCID: https://orcid.org/0000-0003-3167-7391)
- Wu Zhang
Institutions
- Simcere Pharmaceutical (China) (CN)
- Zhejiang Shuren University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36405
- Citations
- 5
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- National Key Research and Development Program of China
- Natural Science Foundation of Zhejiang Province
- Science and Technology Program of Zhejiang Province