One side effect: two networks? Lateral and posteromedial stimulation spreads induce dysarthria in subthalamic deep brain stimulation for Parkinson’s disease
This study reveals an involvement of both, cerebello-thalamic fibres, as well as the pyramidal tract, in the pathogenesis of SID in STN-DBS. The results may impact future postoperative programming strategies to avoid SID in patients with PD and STN-DBS TRIAL REGISTRATION NUMBER: DRKS00023221; German Clinical Trials Register (DRKS) Number.
Authors
- Joshua N. Strelow (ORCID: https://orcid.org/0000-0002-2194-5930)
- Veerle E. R. M. Visser-Vandewalle (ORCID: https://orcid.org/0000-0002-5274-7929)
- Gereon R. Fink (ORCID: https://orcid.org/0000-0002-8230-1856)
- Ilona Rubi‐Fessen (ORCID: https://orcid.org/0000-0002-9775-3812)
- Doris Mücke (ORCID: https://orcid.org/0000-0002-6217-3121)
- Hannah Jergas (ORCID: https://orcid.org/0000-0003-3041-1583)
- Tabea Thies (ORCID: https://orcid.org/0000-0001-9149-3143)
- Jonathan Hannemann
- Jan Niklas Petry‐Schmelzer (ORCID: https://orcid.org/0000-0003-0749-3840)
- Till A. Dembek (ORCID: https://orcid.org/0000-0001-7023-146X)
- Juan Carlos Baldermann (ORCID: https://orcid.org/0000-0001-5851-9268)
- Michael T. Barbe (ORCID: https://orcid.org/0000-0003-1149-8054)
- Jana Quinting (ORCID: https://orcid.org/0000-0002-2153-6432)
Institutions
- University of Cologne (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1136/jnnp-2024-333434
- Citations
- 10
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.69