Influence of casein on the degradation process of polylactide-casein coatings for resorbable alloys
This study used the dip-coating method to develop a new biocompatible coating composed of polylactide (PLA) and casein for ZnMg1.2 wt% alloy implants. It evaluated its impact on the alloy's degradation in a simulated body fluid. After 168 h of immersion in Ringer's solution, surface morphology analysis showed that the PLA-casein coatings demonstrated uniform degradation, with the corrosion current density measured at 48 µA/cm<sup>2</sup>. Contact angle measurements indicated that the average contact angles for the PLA-casein-coated samples were below 80°, signifying a hydrophilic nature that promotes cell adhesion. Fourier-transform infrared spectroscopy (FTIR) revealed no presence of lactic acid on PLA-casein coatings after immersion, in contrast to pure PLA coatings. Pull-off adhesion tests showed tensile strength values of 7.6 MPa for pure PLA coatings and 5 MPa for PLA-casein coatings. Electrochemical tests further supported the favorable corrosion resistance of the PLA-casein coatings, highlighting their potential to reduce tissue inflammation and improve the biocompatibility of ZnMg1.2 wt% alloy implants.
Authors
- Tansel Tunçay (ORCID: https://orcid.org/0000-0002-7762-8504)
- Marcin Staszuk (ORCID: https://orcid.org/0000-0003-3637-9713)
- Katarzyna Cesarz-Andraczke (ORCID: https://orcid.org/0000-0001-9636-4869)
- Weronika Smok (ORCID: https://orcid.org/0000-0003-0786-0620)
- Anna Woźniak (ORCID: https://orcid.org/0000-0002-0144-1321)
- Badegül Tunçay
Institutions
- Silesian University of Technology (PL)
- Karabük University (TR)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1038/s41598-024-69956-6
- Citations
- 2
- Primary Topic
- biodegradable polymer synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.35
Funders
- Silesian University of Technology