Repeated exposure to novelty promotes resilience against the amyloid-beta effect through dopaminergic stimulation
These compelling results demonstrate the potential for repeated novelty exposure to strengthen the dopaminergic system and mitigate the toxic effects of Aβ<sub>1-42</sub>. They also highlight new and promising therapeutic avenues for treating and preventing AD, especially in its early stages.
Authors
- Miguel Tapia‐Rodríguez (ORCID: https://orcid.org/0000-0002-2248-6596)
- Federico Bermúdez‐Rattoni (ORCID: https://orcid.org/0000-0003-2056-6119)
- Eduardo Hernández-Ortiz (ORCID: https://orcid.org/0000-0003-1503-4097)
- Perla Moreno‐Castilla (ORCID: https://orcid.org/0000-0001-8066-9078)
- Lucía Landa‐Navarro (ORCID: https://orcid.org/0009-0005-7627-8433)
- Cintia Velázquez-Delgado
Institutions
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1007/s00213-024-06650-5
- Citations
- 5
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Consejo Nacional de Ciencia y Tecnología
- Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México