Contamination of the traditional medicine Radix Dipsaci with aflatoxin B1 impairs hippocampal neurogenesis and cognitive function in a mouse model of osteoporosis
Contamination of Radix Dipsaci with aflatoxin B1 not only eliminates the herbal decoction's anti-osteoporotic effects, but it also induces neurotoxicity that can lead to cognitive decline and behavioral abnormalities. Such contamination should be avoided through tightly regulated production and quality control of medicinal herbs.
Authors
- Cheng Peng
- Chuanzhi Kang (ORCID: https://orcid.org/0000-0002-2758-4785)
- Dapeng Su
- Qing‐Song Yuan (ORCID: https://orcid.org/0000-0002-9713-099X)
- Jinqiang Zhang (ORCID: https://orcid.org/0000-0003-1563-827X)
- Lulu Wang (ORCID: https://orcid.org/0000-0001-7507-4141)
- Tao Zhou (ORCID: https://orcid.org/0000-0001-8508-9355)
- Chengyan Yang (ORCID: https://orcid.org/0009-0008-2479-5502)
- Weike Jiang (ORCID: https://orcid.org/0000-0003-3291-5064)
- Chenghong Xiao
- Changgui Yang
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guizhou University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2024-08-15
- DOI
- https://doi.org/10.1016/j.ecoenv.2024.116831
- Citations
- 3
- Primary Topic
- Immunotoxicology and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.72