RISKS RELATED TO DIAZEPINE DEPENDENCE AND WITHDRAWAL MANAGEMENT: LITERATURE REVIEW
Introduction:The chronic use of diazepine medication is increasing and, in addition, without a prescription or adequate medical prescription.It leads to changes in the GABA receptor, reducing its affinity for its neurotransmitter and decreasing GABAergic activity.This is manifested in the form of tolerance to the drug (MOSFIAK, 2020).Objective: To review the risks related to diazepine dependence and management of its withdrawal.Result: Unfortunately, there is still no robust evidence that any medication can be used to aid withdrawal from diazepines after prolonged use, although some research and reviews have been carried out in this regard (MOSFIAK, 2020).Conclusion: The chronic use of diazepine medication is increasing and, in addition, without a prescription or adequate medical prescription.It leads to changes in the GABA receptor, reducing its affinity for its neurotransmitter and decreasing GABAergic activity.This is manifested in the form of tolerance to the drug (MOSFIAK, 2020).
Authors
- Aline Galdino Goiz
- Samanttha Cristina da Silva Chaves
- Anny Izumi Toma
- Layo Abreu Machado
- Ayumi Fukuyama Parra
- Sarah Frota Loiola
- Laura Oliveira Lorenzo de Andrade
- Paulo Henrique Faria Domingues
- Alciléa Barbosa de Andrade Vila Flor
- Luiz Gustavo De Sant’Anna Santos
- Flávio Henrique Alves
- Mainara de Queiroz Moreira
- Elma Oliveira Alves Monteiro
Institutions
- Universidade Estadual de Maringá (BR)
- Universidade Federal da Grande Dourados (BR)
- Universidade Metropolitana de Santos (BR)
- Universidade Presidente Antônio Carlos (BR)
Publication Details
- Journal
- International Journal of Health Science
- Published
- 2024-08-12
- DOI
- https://doi.org/10.22533/at.ed.1594752412087
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 0.00