Antifungal Activity of the Dichloromethane Extract of CaoHuangGuiXiang Formula Against Candida auris by in vitro and in vivo Evaluation
CHGX-DME exhibited potent antifungal activity against <i>C. auris</i> and significantly ameliorated this fungal infection in the <i>G. mellonella</i> model, confirming that it would be a promising antifungal drug for the troublesome and emerging fungal pathogen <i>C. auris</i>.
Authors
- Xiaolong Xu (ORCID: https://orcid.org/0000-0003-3333-0906)
- Huizhen Yue (ORCID: https://orcid.org/0009-0001-4618-308X)
- Shuo Wang (ORCID: https://orcid.org/0000-0001-6830-0817)
- Qingquan Liu (ORCID: https://orcid.org/0000-0002-0037-290X)
- Shengnan Zhang
- Xuanyu Wang (ORCID: https://orcid.org/0009-0003-2640-3086)
- Maifen Song (ORCID: https://orcid.org/0009-0005-1735-6091)
- Bing Peng
- Jinhao Tian
Institutions
- Beijing University of Chinese Medicine (CN)
- Capital Medical University (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/idr.s467418
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- National Natural Science Foundation of China