Species Similarity of Corneal Collagen in Grafts of Animal Origin

The species similarity of corneal collagen in animal grafts was studied using small-angle X-ray scattering and Raman spectroscopy. Detailed analysis of the Raman spectra in the range of 1500–1700 cm–1 for human, porcine, and horse grafts demonstrated that bands associated with proteins and amino acids do not exhibit obvious differences in the structure of corneal grafts. Parameters of the internal structure of collagen obtained from scattering spectra also indicate the species similarity of corneal collagen in grafts. Satisfactory results of layer-by-layer intralamellar implantation of porcine and horse grafts “Corneoplast” are presented.

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Publication Details

Journal
Physics of Particles and Nuclei Letters
Published
2024-08-01
DOI
https://doi.org/10.1134/s1547477124701462
Primary Topic
Corneal Surgery and Treatments
Type
article
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article

Species Similarity of Corneal Collagen in Grafts of Animal Origin

Yu. E. Gorshkova, И. П. Попов, С. И. Анисимов, M. P. Orlova et al.
Physics of Particles and Nuclei Letters
Corneal Surgery and Treatments
article

Species Similarity of Corneal Collagen in Grafts of Animal Origin

Yu. E. Gorshkova, И. П. Попов, С. И. Анисимов, M. P. Orlova, N. Yu. Anisimova, M. Naumenko, O. Lis
article en

Abstract

The species similarity of corneal collagen in animal grafts was studied using small-angle X-ray scattering and Raman spectroscopy. Detailed analysis of the Raman spectra in the range of 1500–1700 cm–1 for human, porcine, and horse grafts demonstrated that bands associated with proteins and amino acids do not exhibit obvious differences in the structure of corneal grafts. Parameters of the internal structure of collagen obtained from scattering spectra also indicate the species similarity of corneal collagen in grafts. Satisfactory results of layer-by-layer intralamellar implantation of porcine and horse grafts “Corneoplast” are presented.

Physics of Particles and Nuclei LettersVol. 21(4)
Moscow State University of Medicine and Dentistry (RU), Kazan Federal University (RU), Joint Institute for Nuclear Research (RU), Helmholtz Moscow Research Institute of Eye Diseases (RU), Institute of Physics (RU)
Zero hunger
Openalex Percentile: Top 78%
Corneal Surgery and Treatments
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