Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice
These data obtained in a mouse model point to the complex effects of POPs on the host and microbiota, providing strong evidence that early life, short-term, and self-limiting POP exposure can adversely impact the microbiome, with effects persisting into later life with associated health implications. https://doi.org/10.1289/EHP13356.
Authors
- Imhoi Koo (ORCID: https://orcid.org/0000-0002-5816-0627)
- Shigetoshi Yokoyama (ORCID: https://orcid.org/0000-0003-4175-0548)
- Seth T. Walk (ORCID: https://orcid.org/0000-0001-6891-8537)
- Fangcong Dong (ORCID: https://orcid.org/0000-0002-6423-5816)
- Trenton M. Wolfe (ORCID: https://orcid.org/0009-0002-8289-5970)
- Yuan Tian (ORCID: https://orcid.org/0000-0001-6174-3359)
- Iain A. Murray (ORCID: https://orcid.org/0000-0003-1535-375X)
- Bipin Rimal (ORCID: https://orcid.org/0000-0001-6528-5156)
- Jordan E. Bisanz (ORCID: https://orcid.org/0000-0002-8649-1706)
- Andrew D. Patterson (ORCID: https://orcid.org/0000-0003-2073-0070)
- Peter J. Turnbaugh (ORCID: https://orcid.org/0000-0002-0888-2875)
- Gary H. Perdew (ORCID: https://orcid.org/0000-0001-6288-8445)
- Shaneice K. Nettleford
- С. А. Кошкин (ORCID: https://orcid.org/0000-0002-4699-1212)
- Wei Gui
- K. Sandeep Prabhu (ORCID: https://orcid.org/0000-0003-0644-1512)
Institutions
- Pennsylvania State University (US)
- University of California, San Francisco (US)
- Montana State University (US)
- Chan Zuckerberg Initiative (United States) (US)
Publication Details
- Journal
- Environmental Health Perspectives
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1289/ehp13356
- Citations
- 8
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- U.S. Department of Agriculture
- Pennsylvania Department of Health
- National Institutes of Health
- Huck Institutes of the Life Sciences