Long non‐coding RNA TPT1‐AS1 inhibits ferroptosis in ovarian cancer by regulating GPX4 via CREB1 regulation

TPT1-AS1 promotes OC progression by inhibiting ferroptosis and upregulating CREB1, forming a regulatory axis with KHDRBS3. These findings highlight the regulatory network involving lncRNAs, RBPs, and transcription factors in cancer progression.

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Publication Details

Journal
American Journal of Reproductive Immunology
Published
2024-08-01
DOI
https://doi.org/10.1111/aji.13864
Citations
5
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
1.43
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article

Long non‐coding RNA TPT1‐AS1 inhibits ferroptosis in ovarian cancer by regulating GPX4 via CREB1 regulation

X.M. Chi, Xiaoying Bai, Juanni Liu, Lei Cao et al.
5 citations
American Journal of Reproductive Immunology
Cancer-related molecular mechanisms research
1.43
article

Long non‐coding RNA TPT1‐AS1 inhibits ferroptosis in ovarian cancer by regulating GPX4 via CREB1 regulation

X.M. Chi, Xiaoying Bai, Juanni Liu, Lei Cao, Yan Wang
article en
5 citations

Abstract

TPT1-AS1 promotes OC progression by inhibiting ferroptosis and upregulating CREB1, forming a regulatory axis with KHDRBS3. These findings highlight the regulatory network involving lncRNAs, RBPs, and transcription factors in cancer progression.

American Journal of Reproductive ImmunologyVol. 92(2)
Affiliated Hospital of Taishan Medical University (CN), Xi'an Medical University (CN), Shandong First Medical University (CN)
Life below water
Openalex Percentile: Top 18%
Cancer-related molecular mechanisms research
1.43
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