Plant-derived compounds normalize platelet bioenergetics and function in hyperglycemia
Our results suggest polyphenols attenuate increased platelet activity stemming from hyperglycemia and may benefit thrombosis-preventative strategies in patients with diabetes.
Authors
- Robert A.S. Ariëns (ORCID: https://orcid.org/0000-0002-6310-5745)
- Abigail Ajanel (ORCID: https://orcid.org/0000-0002-4601-3769)
- Amanda D. V. MacCannell (ORCID: https://orcid.org/0000-0002-1294-5250)
- Julia S. Gauer (ORCID: https://orcid.org/0000-0002-0835-639X)
- Lee D. Roberts (ORCID: https://orcid.org/0000-0002-1455-5248)
- Lutale M. Kaselampao
- Isabel Candir
- Robert A. Campbell
Institutions
- University of Leeds (GB)
- Washington University in St. Louis (US)
- University of Utah (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.rpth.2024.102548
- Citations
- 3
- Primary Topic
- Pharmacology and Obesity Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.34
Funders
- American Society of Hematology
- Wellcome Trust
- International Society on Thrombosis and Haemostasis
- National Institute for Health and Care Research
- British Heart Foundation
- Department of Health and Social Care
- Diabetes UK
- National Institutes of Health
- Directorate for Biological Sciences
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- Leeds Biomedical Research Centre