LncRNA ILF3‐AS1 mediates oxidative stress and inflammation through miR‐504‐3p/HMGB1 axis in a cellular model of temporal lobe epilepsy
Our findings indicate that ILF3-AS1 contributes to Mg<sup>2+</sup>-free-induced hippocampal neuron injuries, oxidative stress, and inflammation by targeting the miR-504-3p/HMGB1 axis. These results provide a novel mechanistic understanding of ILF3-AS1 in TLE and suggest potential therapeutic targets for the treatment of epilepsy.
Authors
- Peipei Gao
- Zhixin Yan (ORCID: https://orcid.org/0000-0001-6448-4110)
- Ying Wu (ORCID: https://orcid.org/0009-0006-0584-460X)
Institutions
- Cangzhou Central Hospital (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/brb3.3615
- Citations
- 6
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Health Commission of Hebei Province