Successful immunosuppressive drug‐free immune tolerance induction in hemophilia B with inhibitor and anaphylaxis to factor <scp>IX</scp>: A case report
Recommendations advise factor IX desensitization before immune tolerance induction in severe hemophilia B, supported by immunosuppression. A child with inhibitor and anaphylaxis to factor IX showed successful immunosuppression-free immune tolerance induction using very low and slowly increasing doses of a factor IX extended-half-life product. Immune tolerance to factor IX based on this protocol merits further study.
Authors
- Ángeles Palomo Bravo (ORCID: https://orcid.org/0000-0002-8793-7378)
- Ihosvany Fernández Bello (ORCID: https://orcid.org/0000-0001-7822-8900)
- Francisco José López‐Jaime (ORCID: https://orcid.org/0000-0003-2407-3901)
- Daniel Bardan Rebollar
- Rosario Prieto Bonilla
Institutions
- Hospital Regional Universitario de Málaga (ES)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/ccr3.9312
- Citations
- 2
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91