Alterations of contralesional hippocampal subfield volumes and relations to cognitive functions in patients with unilateral stroke
Unilateral stroke caused volumetric differences in different hippocampal subfields contralesionally, which correlated to cognitive impairment. RHS leads to greater volumetric reduction in the whole contralesional hippocampus and specific subfields (hippocampal tail, CA1, ML, GC-ML-DG, CA3, and CA4) compared to LHS. These changes are correlated with cognitive impairments, potentially due to disrupted neural pathways and interhemispheric communication.
Authors
- Xu‐Yun Hua (ORCID: https://orcid.org/0000-0002-2935-7551)
- Xiang‐Xin Xing
- Jia‐Jia Wu (ORCID: https://orcid.org/0000-0001-7515-3958)
- Jian‐Guang Xu (ORCID: https://orcid.org/0000-0003-0601-3403)
- Mou‐Xiong Zheng (ORCID: https://orcid.org/0000-0002-9861-6086)
- Juan‐Juan Lu
- Jiao Qu
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Songjiang District Central Hospital (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/brb3.3645
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Shanghai Rising-Star Program
- National Key Research and Development Program of China