Anti‐Ri‐antibodies associated paraneoplastic myelopathy revealing a woman's breast cancer: A case report

Abstract Paraneoplastic myelopathy (PM) is an enigmatic immune‐mediated disorder rarely associated with breast cancer (BC) and anti‐Ri antibodies. Sometimes diagnosis is difficult due to the heterogeneity of symptoms and the timing of their onset. Herein, we report the case of a woman presenting with cervical myelopathy causing spastic left hemiplegia and painful spasms. Diagnosis of PM was confirmed through the positivity of well‐characterized onconeural antibodies (anti‐Ri) and the discovery of BC after a clinical examination and multiple investigations. We highlight, through this case, the importance of onconeural antibodies in the diagnosis of paraneoplastic neurological syndromes and associated cancer.

Authors

Institutions

Publication Details

Journal
Neurology and Clinical Neuroscience
Published
2024-08-12
DOI
https://doi.org/10.1111/ncn3.12850
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Anti‐Ri‐antibodies associated paraneoplastic myelopathy revealing a woman's breast cancer: A case report

Rania Zouari, Jihen Abdellatif, Ahlem Ben Hmid, Mèlika Ben Ahmed et al.
Neurology and Clinical Neuroscience
Autoimmune Neurological Disorders and Treatments
article

Anti‐Ri‐antibodies associated paraneoplastic myelopathy revealing a woman's breast cancer: A case report

Rania Zouari, Jihen Abdellatif, Ahlem Ben Hmid, Mèlika Ben Ahmed, Imen Zamali, Samia Ben Sassi, Mohamed Zakaria Saeid
article en

Abstract

Abstract Paraneoplastic myelopathy (PM) is an enigmatic immune‐mediated disorder rarely associated with breast cancer (BC) and anti‐Ri antibodies. Sometimes diagnosis is difficult due to the heterogeneity of symptoms and the timing of their onset. Herein, we report the case of a woman presenting with cervical myelopathy causing spastic left hemiplegia and painful spasms. Diagnosis of PM was confirmed through the positivity of well‐characterized onconeural antibodies (anti‐Ri) and the discovery of BC after a clinical examination and multiple investigations. We highlight, through this case, the importance of onconeural antibodies in the diagnosis of paraneoplastic neurological syndromes and associated cancer.

Neurology and Clinical NeuroscienceVol. 13(1)
Tunis University (TN), Institut Pasteur de Tunis (TN), National Institute of Neurology Mongi-Ben Hamida (TN), Faculté de médecine de Tunis
Good health and well-being
Openalex Percentile: Top 80%
Autoimmune Neurological Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.