A Biomimetic Nanocarrier Strategy Targets Ferroptosis and Efferocytosis During Myocardial Infarction

Our results demonstrated that the cooperation between the two agents induced anti-ferroptosis effects and enhanced dead cardiomyocyte clearance by macrophage as well as anti-inflammation effects. Thus, our nanoparticle Fer-aCD47@PHMSN provides a new therapeutic strategy for targeted therapy of MI.

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Publication Details

Journal
International Journal of Nanomedicine
Published
2024-08-01
DOI
https://doi.org/10.2147/ijn.s461212
Citations
13
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
3.04
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article

A Biomimetic Nanocarrier Strategy Targets Ferroptosis and Efferocytosis During Myocardial Infarction

Weiwei Wu, Lin Song, Pincheng Wang, Jianxun Wang et al.
13 citations
International Journal of Nanomedicine
Extracellular vesicles in disease
3.04
article

A Biomimetic Nanocarrier Strategy Targets Ferroptosis and Efferocytosis During Myocardial Infarction

Weiwei Wu, Lin Song, Pincheng Wang, Jianxun Wang, Xiaosu Yuan, Zhonghao Zhao
article en
13 citations

Abstract

Our results demonstrated that the cooperation between the two agents induced anti-ferroptosis effects and enhanced dead cardiomyocyte clearance by macrophage as well as anti-inflammation effects. Thus, our nanoparticle Fer-aCD47@PHMSN provides a new therapeutic strategy for targeted therapy of MI.

International Journal of NanomedicineVol. Volume 19
Qingdao University (CN)
Zero hunger
Openalex Percentile: Top 8%
Extracellular vesicles in disease
3.04
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