Assessment of immunopathological responses of a novel non-chemical biocide in C57BL/6 for safe disinfection usage
The results of this study suggest that WE is a safe technology for disinfecting airborne pathogens. It demonstrated little to no effect on immune system activation and pathological outcomes in the intranasal challenge C57BL/6 mouse model. These findings not only support the potential use of WE as an effective and safe method for air disinfection but also highlight the value of the intranasal challenge of the C57BL/6 mouse model in providing significant immunopathological insights for assessing the inhalation of novel materials for potential use.
Authors
- Keun Bon Ku (ORCID: https://orcid.org/0000-0003-0870-0995)
- Heung Kyu Lee (ORCID: https://orcid.org/0000-0002-3977-1510)
- Jeongwoo La (ORCID: https://orcid.org/0000-0002-8153-7402)
- Sang Eon Lee (ORCID: https://orcid.org/0000-0002-7076-9638)
- Won Hyung Park (ORCID: https://orcid.org/0000-0002-6824-2423)
- J. S. Chae
Institutions
- Korea Advanced Institute of Science and Technology (KR)
- Korea Research Institute of Chemical Technology (KR)
Publication Details
- Journal
- Laboratory Animal Research
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1186/s42826-024-00214-6
- Primary Topic
- Infection Control and Ventilation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea