Neuroprotective effects of GPR68 against cerebral ischemia-reperfusion injury via the NF-κB/Hif-1α pathway
This study confirms that the GPR68/NF-κB/Hif-1α axis modulates apoptosis, inflammation, and oxidative stress in CIRI, indicating that GPR68 is a potential therapeutic target for CIRI.
Authors
- Kaiguo Xia (ORCID: https://orcid.org/0000-0002-6795-6547)
- Fubing Yang
- Chuanhong Zhong (ORCID: https://orcid.org/0000-0002-1436-4062)
- Xianglong Li
- You Jian (ORCID: https://orcid.org/0000-0002-7228-7042)
- Xiangzhou Chen
- Ligang Chen (ORCID: https://orcid.org/0000-0003-2752-0244)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- First Affiliated Hospital of Sichuan Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1016/j.brainresbull.2024.111050
- Citations
- 8
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.98
Funders
- Department of Science and Technology of Sichuan Province
- Southwest Medical University
- Affiliated Hospital of Southwest Medical University