The spatial distribution of intermediate fibroblasts and myeloid-derived cells dictate lymph node metastasis dynamics in oral cancer
We have generated a functional organization of the tumor-stromal interface in GB-OSCC and identified spatially located genes that contribute to nodal metastasis and disease progression. Our dataset might now be mined to discover suitable molecular targets in oral cancer.
Authors
- Devmalya Banerjee (ORCID: https://orcid.org/0000-0001-9822-3664)
- Sangramjit Basu
- Harsh Dhar (ORCID: https://orcid.org/0000-0003-0508-818X)
- Geetashree Mukherjee (ORCID: https://orcid.org/0000-0003-4954-0035)
- Soni Shaikh (ORCID: https://orcid.org/0000-0002-9260-0577)
- Deepak Kumar Mishra (ORCID: https://orcid.org/0000-0002-7244-8280)
- M. Moorthy (ORCID: https://orcid.org/0009-0002-5282-9147)
- Sourav Datta (ORCID: https://orcid.org/0000-0002-7604-8444)
- Vijayalakshmi Bhat
Institutions
- Tata Medical Center (IN)
- Nethradhama Superspeciality Eye Hospital (IN)
- Tata Consultancy Services (India) (IN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1186/s12967-024-05511-1
- Citations
- 6
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Department of Biotechnology, Ministry of Science and Technology, India