Discrepancy Between Genetically Predicted and Observed BMI Predicts Incident Type 2 Diabetes

Having a higher BMI than genetically predicted is associated with an increased risk of T2D. These findings underscore the potential to reassess T2D risk based on individual levels of obesity using genetic thresholds for BMI.

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Publication Details

Journal
Diabetes Care
Published
2024-08-13
DOI
https://doi.org/10.2337/dc24-0879
Citations
9
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
4.95

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article

Discrepancy Between Genetically Predicted and Observed BMI Predicts Incident Type 2 Diabetes

Soo Heon Kwak, Jun‐Bean Park, J. Merino, Jaewon Choi et al.
9 citations
Diabetes Care
Genetic Associations and Epidemiology
4.95
article

Discrepancy Between Genetically Predicted and Observed BMI Predicts Incident Type 2 Diabetes

Soo Heon Kwak, Jun‐Bean Park, J. Merino, Jaewon Choi, Hyunsuk Lee, Tae-Min Rhee
article en
9 citations

Abstract

Having a higher BMI than genetically predicted is associated with an increased risk of T2D. These findings underscore the potential to reassess T2D risk based on individual levels of obesity using genetic thresholds for BMI.

Diabetes CareVol. 47(10)
University of Copenhagen (DK), Seoul National University (KR), Novo Nordisk Foundation (DK), Seoul National University Hospital (KR)
National Research Foundation, Ministry of Food and Drug Safety, Korea Health Industry Development Institute, National Research Foundation of Korea, Novo Nordisk, Novo Nordisk Foundation Center for Basic Metabolic Research, Ministry of Science and ICT, South Korea, Centers for Disease Control and Prevention, National Human Genome Research Institute
Good health and well-being
Openalex Percentile: Top 5%
Genetic Associations and Epidemiology
4.95
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