Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems

Synthesis of analogs of known active compounds is the most often employed strategy for producing important compounds. The Hantzsch reaction was employed to create new star-shaped compounds with a pentaerythritol core connected to thiazoles, hexahydroacridinediones, decahydropyrimido[4,5- b ]quinolones, and tetrahydro[1,2,4]triazolo[5,1- b ]quinazoline in this study. The flexible precursor was 4′-((2,2-bis((4-formylphenoxy)methyl)propane-1,3-diyl)bis(oxy))dibenzaldehyde. Under milder reaction conditions, the target compounds were produced with high yields as well as shorter reaction times. The structures of the new compounds were established using elemental analysis and spectral data.

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Publication Details

Journal
Results in Chemistry
Published
2024-08-01
DOI
https://doi.org/10.1016/j.rechem.2024.101726
Citations
4
Primary Topic
Dendrimers and Hyperbranched Polymers
Type
article
Field-Weighted Citation Impact
0.67
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article

Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems

Hadeer M. Diab, Ismail A. Abdelhamid, Magdi E. A. Zaki, Mostafa E. Salem et al.
4 citations
Results in Chemistry
Dendrimers and Hyperbranched Polymers
0.67
article

Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems

Hadeer M. Diab, Ismail A. Abdelhamid, Magdi E. A. Zaki, Mostafa E. Salem, Amr M. Abdelmoniem, Ahmed H. M. Elwahy, Islam Ragab
article en
4 citations

Abstract

Synthesis of analogs of known active compounds is the most often employed strategy for producing important compounds. The Hantzsch reaction was employed to create new star-shaped compounds with a pentaerythritol core connected to thiazoles, hexahydroacridinediones, decahydropyrimido[4,5- b ]quinolones, and tetrahydro[1,2,4]triazolo[5,1- b ]quinazoline in this study. The flexible precursor was 4′-((2,2-bis((4-formylphenoxy)methyl)propane-1,3-diyl)bis(oxy))dibenzaldehyde. Under milder reaction conditions, the target compounds were produced with high yields as well as shorter reaction times. The structures of the new compounds were established using elemental analysis and spectral data.

Results in ChemistryVol. 10
Cairo University (EG), Qassim University (SA), Imam Mohammad ibn Saud Islamic University (SA)
Openalex Percentile: Top 38%
Dendrimers and Hyperbranched Polymers
0.67
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