تقييم مضادات الميكروبات مضادات الأكسدة والمحتوى الكلي للفينولات لمستخلصات السنا سنا في السودان

The objective of the present study was the assessment of the antimicrobial and antioxidant activities of Senna italic., from n-hexane, chloroform, ethyl acetate and methanol extracts. In addition, the total polyphenol, flavonoids and tannins contents of these extracts were determined and; were screened for their antimicrobial activity using cup diffusion assay against four standard strains of bacteria, two Gram-positive strains (Bacillus subtitles and Staphylococcus aurous), two Gram-negative bacterial strains (Escherichia coli and Pseudomonas aeruginosa) and two fungal strains (Aspergillums Niger and Candida barbicans). Antioxidant activity was screened using 2,2-Di(4-tert-octylphenyl)-1-picryl-hydrazyl stable free radical (DPPH). Total polyphenol, flavonoids and tannins contents were determined by spectrophotometric assays. Generally, the results of antimicrobial activity showed that extracts of the plant exhibited better antifungal activity than antibacterial.