Platelet margination dynamics in blood flow: The role of lift forces and red blood cells aggregation
The presence of platelets near vessel walls is crucial for clot formation to stop bleeding. We examine platelet margination influenced by red blood cell (RBC) aggregation through numerical simulation. Our findings indicate that moderate to strong RBC aggregation enhances platelet margination in microcirculation, thereby improving the capacity to stop bleeding. This mechanism offers a natural counteraction against major bleeding in conditions such as diabetes, where strong RBC aggregation is commonly observed.
Authors
- Mehdi Abbasi (ORCID: https://orcid.org/0000-0003-0135-2692)
- Chaouqi Misbah (ORCID: https://orcid.org/0000-0001-5793-8102)
- Hamid Ez-Zahraouy (ORCID: https://orcid.org/0009-0007-1888-2741)
- Mariam Dynar
Institutions
- Mohammed V University (MA)
- Centre National de la Recherche Scientifique (FR)
- Aix-Marseille Université (FR)
- Institut des langues et cultures d'Europe, Amérique, Afrique, Asie et Australie (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- Physical Review Fluids
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1103/physrevfluids.9.083603
- Citations
- 1
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Centre National d’Etudes Spatiales