Alantolactone alleviates epithelial-mesenchymal transition by regulating the TGF-β/STAT3 signaling pathway in renal fibrosis
Alantolactone improves EMT in RTECs by inhibiting STAT3 phosphorylation and Twist expression, suggesting its potential as a therapeutic agent for kidney fibrosis.
Authors
- Yeo Jin Hwang (ORCID: https://orcid.org/0000-0002-8031-7686)
- Gwon‐Soo Jung
- Kyeong‐Min Lee (ORCID: https://orcid.org/0000-0002-3962-131X)
Institutions
- Daegu Gyeongbuk Institute of Science and Technology (KR)
- Daegu-Gyeongbuk Medical Innovation Foundation (KR)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36253
- Citations
- 3
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 1.65
Funders
- National Research Foundation
- National Research Foundation of Korea
- Daegu Gyeongbuk Institute of Science and Technology