Evaluating potential unexpected adverse events and mortality after oral analgesics administration in fracture care-a cohort study
Data suggest that oral acetaminophen added tramadol combined with any of pregabalin, diclofenac, etoricoxib, or gabapentin might increase the death risk or unexpected serious adverse events in elderly diabetic and hypertensives suffering from intertrochanteric/femoral neck fracture. Safe analgesic selection is necessitated for at-risk patients.
Authors
- Zehra Abdul Muhammad (ORCID: https://orcid.org/0000-0002-6048-9042)
- Tashfeen Ahmad (ORCID: https://orcid.org/0000-0002-8046-3974)
- Haroon Rashid (ORCID: https://orcid.org/0000-0002-4981-0632)
Institutions
- Aga Khan University (PK)
Publication Details
- Journal
- Expert Opinion on Drug Safety
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1080/14740338.2024.2392863
- Citations
- 1
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.45
Funders
- Orthopaedic Trauma Association