Formulation and evaluation of novel herbal antidiabetic nutraceutical powder dosage using edible plant components of Tripura, India

Nutritional deficiency diseases are common in India and other developing countries. Recently, herbal nutraceutical products have diminished diseases related to nutrition and improper diet. The current study aimed to develop a powdered herbal nutraceutical using certain native edible plant parts from Tripura, India, and to assess its antidiabetic activity. Plant parts were selected based on the ethnomedicinal information of healers. Nutraceutical powder was prepared by a simple mixing method using a double cone blender. Bulk density, tapped density, Hausner quotient, Carr’s compressibility index, flow rate, and angle of repose were determined to evaluate the nutraceutical powder. The proximate composition was determined by The Association of Official Analytical Collaboration (AOAC) methods. Essential minerals were determined using an atomic absorption spectrophotometer (AAS). Vitamins (vit-C, vit-B9, vit-A, and vit-E) were determined using HPLC. The anti-diabetic activity of the nutraceutical powder was evaluated by the Oral Glucose Tolerant (OGTT) test. All selected plants provided significant ethnomedicinal information. All physical parameters of the nutraceutical powder significantly matched the standard values. The formulated nutraceutical powder had a good caloric value (369 kcal), and a good amount of minerals and vitamins were found. Formulated nutraceutical powder shows significant antidiabetic activity. Based on the results, it was concluded that formulated nutraceutical powder may minimize various malnutritional diseases and control the blood glucose label.