Screening and identification of nanobody against inhibin α-subunit from a Camelus bactrianus phage display library

Four inhibin α-subunit-specific nanobodies with biological functions were successfully screened. To the best of our knowledge, this is a new reproductive immunomodulatory pathway of inhibin α-subunit, which may change the secretion of FSH in the ovary, thus changing the estrous cycle of organisms.

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Publication Details

Journal
Heliyon
Published
2024-08-12
DOI
https://doi.org/10.1016/j.heliyon.2024.e36180
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Screening and identification of nanobody against inhibin α-subunit from a Camelus bactrianus phage display library

Jifu Ma, Kezerbek Khalembek, Bakhet Bodai, Rizabek Kadyken et al.
Heliyon
Monoclonal and Polyclonal Antibodies Research
article

Screening and identification of nanobody against inhibin α-subunit from a Camelus bactrianus phage display library

Jifu Ma, Kezerbek Khalembek, Bakhet Bodai, Rizabek Kadyken, Jingang Xie, Oralhazi Kazkhan, Mukhtar Baibatshanov, Zhongmei Ma
article en

Abstract

Four inhibin α-subunit-specific nanobodies with biological functions were successfully screened. To the best of our knowledge, this is a new reproductive immunomodulatory pathway of inhibin α-subunit, which may change the secretion of FSH in the ovary, thus changing the estrous cycle of organisms.

HeliyonVol. 10(17)
Shihezi University (CN), Altaiskiy State Nature Biosphere Reserve (RU), Kazakh National Agrarian Research University (KZ)
Key Program of NSFC-Tongyong Union Foundation, National Natural Science Foundation of China-Yunnan Joint Fund, Xinjiang Academy of Agricultural Sciences, Ministry of Education Science and Technology Industry-University Cooperation and Education Project
Openalex Percentile: Top 82%
Monoclonal and Polyclonal Antibodies Research
DOIOpen Access PDFOpenAlex
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