Increased risk of adverse drug reactions by higher linezolid dose per weight in multidrug-resistant tuberculosis

Linezolid ADRs were frequent in a high-resource setting. Structured, regular follow-up for ADRs and adjusting dosing according to body weight followed-up by monitoring of drug concentrations early may reduce toxicity.

Authors

Institutions

Publication Details

Journal
International Journal of Antimicrobial Agents
Published
2024-08-13
DOI
https://doi.org/10.1016/j.ijantimicag.2024.107302
Citations
9
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
3.50

Funders

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article

Increased risk of adverse drug reactions by higher linezolid dose per weight in multidrug-resistant tuberculosis

Jan‐Willem C. Alffenaar, Thomas Schön, Johanna Kuhlin, Ramona Groenheit et al.
9 citations
International Journal of Antimicrobial Agents
Tuberculosis Research and Epidemiology
3.50
article

Increased risk of adverse drug reactions by higher linezolid dose per weight in multidrug-resistant tuberculosis

Jan‐Willem C. Alffenaar, Thomas Schön, Johanna Kuhlin, Ramona Groenheit, Jerker Jonsson, Judith Bruchfeld, Mikael Mansjö, Jim Werngren, Lina Davies Forsman, Aisha Osman, Magdalena Skagerberg
article en
9 citations

Abstract

Linezolid ADRs were frequent in a high-resource setting. Structured, regular follow-up for ADRs and adjusting dosing according to body weight followed-up by monitoring of drug concentrations early may reduce toxicity.

International Journal of Antimicrobial AgentsVol. 64(4)
Linköping University (SE), The University of Sydney (AU), Public Health Agency of Sweden (SE), Karolinska University Hospital (SE), Sydney Hospital (AU), Karolinska Institutet (SE), Linköping University Hospital (SE)
Hjärt-Lungfonden, Vetenskapsrådet
Good health and well-being
Openalex Percentile: Top 7%
Tuberculosis Research and Epidemiology
3.50
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Increased risk of adverse drug reactions by higher linezolid dose per weight in multidrug-resistant tuberculosis — Jan‐Willem C. Alffenaar, Thomas Schön, et al. · International Journal of Antimicrobial Agents (2024) | TGRS Research Map | TGRS