Leveraging Large Language Models for Precision Monitoring of Chemotherapy-Induced Toxicities: A Pilot Study with Expert Comparisons and Future Directions

This study concludes that LLMs can classify subjective toxicities from chemotherapy with accuracy comparable to expert oncologists. The LLM's performance in general toxicity categories is within the expert range, but there is room for improvement in specific categories. LLMs have the potential to enhance patient monitoring, enable early interventions, and reduce severe complications, improving care quality and efficiency. Future research should involve specific training of LLMs, validation with real patients, and the incorporation of interactive capabilities for real-time patient interactions. Ethical considerations, including data accuracy, transparency, and privacy, are crucial for the safe integration of LLMs into clinical practice.

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Publication Details

Journal
Cancers
Published
2024-08-12
DOI
https://doi.org/10.3390/cancers16162830
Citations
12
Primary Topic
Palliative Care and End-of-Life Issues
Type
article
Field-Weighted Citation Impact
6.52

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article

Leveraging Large Language Models for Precision Monitoring of Chemotherapy-Induced Toxicities: A Pilot Study with Expert Comparisons and Future Directions

María Teresa Pérez Hoyos, Maitane Nuño Escolástico, María Purificación Martínez del Prado, María López-Santillán et al.
12 citations
Cancers
Palliative Care and End-of-Life Issues
6.52
article

Leveraging Large Language Models for Precision Monitoring of Chemotherapy-Induced Toxicities: A Pilot Study with Expert Comparisons and Future Directions

María Teresa Pérez Hoyos, Maitane Nuño Escolástico, María Purificación Martínez del Prado, María López-Santillán, Onintza Sayar Beristain, Laura Sande Sardina, Borja López de San Vicente Hernández, Elena Gálve, Covadonga Figaredo Berjano, M.T. Abad Villar, M.Á. Sala González, Maialen Zabalza Zudaire, Laura Sánchez Togneri, Josune Azcuna Sagarduy, Oskitz Ruiz Sarrias, Pablo Casado Cuesta
article en
12 citations

Abstract

This study concludes that LLMs can classify subjective toxicities from chemotherapy with accuracy comparable to expert oncologists. The LLM's performance in general toxicity categories is within the expert range, but there is room for improvement in specific categories. LLMs have the potential to enhance patient monitoring, enable early interventions, and reduce severe complications, improving care quality and efficiency. Future research should involve specific training of LLMs, validation with real patients, and the incorporation of interactive capabilities for real-time patient interactions. Ethical considerations, including data accuracy, transparency, and privacy, are crucial for the safe integration of LLMs into clinical practice.

CancersVol. 16(16)
Hospital de Basurto (ES), Osakidetza (ES)
Gobierno de Navarra
Peace, Justice and strong institutions
Openalex Percentile: Top 3%
Palliative Care and End-of-Life Issues
6.52
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