Bone marrow disease profile in geriatric patients: An institutional study

Introduction: For the diagnosis and treatment of numerous hematological and non-hematological disorders in patients of all ages, a bone marrow examination is a crucial investigation. Due to the growing elderly population and the paucity of published studies on bone marrow disorders that only affect the elderly, age-related health conditions are becoming more prevalent. In our study, we enrolled elderly patients >60 years old who had a bone marrow examination at GMC Jammu's pathology department.Aim: To study the profile of various hematological and non-hematological lesions diagnosed on Bone Marrow aspiration and/or Trephine biopsy in Geriatric age group 2. To summarize an approach for evaluation of anemia in elderly patients for better management.Materials and Methods : The study was conducted in two parts; a Retrospective study for 4 years and a prospective study of 1 year. It included all the patients >60 years of age who had undergone Bone marrow examination in the hematology section of the Department of Pathology.Results : 200 bone marrow aspirations and 40 trephine biopsies, as well as peripheral blood smears and biopsy imprint smears, were all examined. Aplastic anemia, Megaloblastic anemia, Iron deficiency anemia, chronic disease-related anemia, and ITP were among the non-malignant hematological disorders that affected 50.5% (n=101) of the patients; various hematological malignancies affected 40.5% (n=81) of the patients; and non-hematological malignancies affected 1% (n=2) of the patients. 1% (n=2) of the cases were insufficient, and 7% (n=14) of the cases in which BMA and/or BMB were used for lymphoma staging and follow-up did not show any signs of marrow infiltration.Conclusion: With the growing elderly population in India, it is important to pay more attention to diagnosing and treating easily treatable conditions like anemia as well as enhancing the general health of geriatric patients the elderly, bone marrow aspiration.