Retigabine, a potassium channel opener, restores thalamocortical neuron functionality in a murine model of autoimmune encephalomyelitis
Our results suggest that RTG treatment might robustly mitigate inflammation-induced altered excitability and preserve ascending information processing.
Authors
- Manuela Cerina (ORCID: https://orcid.org/0000-0001-7888-6436)
- Sven Guenther Meuth (ORCID: https://orcid.org/0000-0003-2571-3501)
- Nicole Rychlik (ORCID: https://orcid.org/0000-0002-8327-6015)
- M. Strüber (ORCID: https://orcid.org/0000-0002-3478-0848)
- Thomas Budde (ORCID: https://orcid.org/0000-0002-5263-8183)
- Luca Fazio (ORCID: https://orcid.org/0000-0003-4695-0039)
- Julia Ladewig (ORCID: https://orcid.org/0000-0002-5943-7990)
- Venu Narayanan Naik (ORCID: https://orcid.org/0000-0002-3637-4173)
- Rajeevan Narayanan Therpurakal (ORCID: https://orcid.org/0000-0002-1298-6802)
- Fiorella M. Gomez Osorio
Institutions
- Goethe University Frankfurt (DE)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University of Münster (DE)
- University Hospital Heidelberg (DE)
- University Hospital Münster (DE)
- Central Institute of Mental Health (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2024-08-13
- DOI
- https://doi.org/10.1016/j.bbi.2024.08.023
- Citations
- 4
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Deutsche Forschungsgemeinschaft